Effect of Physical Parameters on the Main Phase Transition of Supported Lipid Bilayers

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Effect of physical parameters on the main phase transition of supported lipid bilayers.

Supported lipid bilayers composed of 1-palmitoyl-2-oleoyl-phosphatidylethanolamine (POPE) and 1-palmitoyl-2-oleoyl-phosphatidylglycerol (POPG) were assembled by the vesicle fusion technique on mica and studied by temperature-controlled atomic force microscopy. The role of different physical parameters on the main phase transition was elucidated. Both mixed (POPE/POPG 3:1) and pure POPE bilayers...

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High pressure effect on phase transition behavior of lipid bilayers.

Phase behavior of lipid bilayers at high pressure is critical to biological processes. Using coarse grained molecular dynamic simulations, we report critical characteristics of dipalmitoylphosphatidylcholine bilayers with applied high pressure, and also show their phase transition by cooling bilayer patches. Our results indicate that the phase transition temperature of dipalmitoylphosphatidylch...

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ژورنال

عنوان ژورنال: Biophysical Journal

سال: 2009

ISSN: 0006-3495

DOI: 10.1016/j.bpj.2009.03.068